Innovative Microscope Poised to Propel Optogenetics Studies

November 30, 2017

The new Firefly microscope is optimized to perform optogenetic studies examining many neurons at once. Each bright spot here represents a neuron from a genetically modified mouse. [Credit: Vaibhav Joshi, Harvard University]

A newly developed microscope is providing scientists with a greatly enhanced tool to study how neurological disorders such as epilepsy and Alzheimer's disease affect neuron communication. The microscope is optimized to perform studies using optogenetic techniques, a relatively new technology that uses light to control and image neurons genetically modified with light-sensitive proteins.

"Our new microscope can be used to explore the effects of different genetic mutations on neuronal function," said Adam Cohen from Harvard University, USA, and the leader of the research team that developed the microscope...

Read more in "Innovative microscope poised to propel optogenetics studies,", November 29, 2017.