Super-mendelian genetics increases the likelihood of inheritance of a desired trait to nearly 100 percent, even if that trait confers a selective disadvantage (Image courtesy of Hidenori Tanaka/Harvard)
So, you’ve genetically engineered a malaria-resistant mosquito, now what? How many mosquitos would you need to replace the disease-carrying wild type? What is the most effective distribution pattern? How could you stop a premature release of the engineered mosquitos?